Ingredients Glossary / D

DNA and RNA

Purified nucleic acid fragments, often from salmon, that help skin hold moisture and look plumper; they don't alter your own DNA.

DNA, RNA, sodium DNA, calcium DNA, magnesium DNA, salmon DNA, triple DNA, nucleic acids, polynucleotides, PDRN

Dry & dehydrated skin · Ageing skin

    What it does

    In skincare, DNA and RNA are purified fragments of nucleic acids, the molecules that carry genetic information in every living cell. Applied to the skin, they have nothing to do with changing your own genetic material. They are valued above all for hydration: they bind water and help the skin hold on to moisture, so it looks plumper, smoother and more rested. They are Valmont's signature actives, at the heart of its formulas.

    How it works

    DNA is a long, water-loving molecule that binds a great deal of water and leaves a light, moisturising film on the skin, much like other large humectants. On labels it appears as sodium DNA; Valmont's “triple DNA” appears as calcium, magnesium and sodium DNA, and its RNA simply as RNA. Commercial DNA is often sourced from salmon, as in Biologique Recherche's Gel ADN Silkgen. Injectable forms (polynucleotides, or PDRN) are a separate, clinician-administered treatment.

    MG says

    Valmont's Triple DNA and RNA are at the heart of The Valmont x Melanie Grant Treatment. At home, I love Prime Regenera II after a long-haul flight, in cold weather or whenever my skin feels dry, stressed or sensitised; I often apply a thick layer as a mask and leave it to infuse for 20 minutes or so.

    Cautions

    Generally well tolerated. DNA in skincare is often derived from fish such as salmon, so check with the brand if you prefer to avoid animal-derived ingredients. Patch test new products if your skin is reactive.

    Regional notes