Ingredients Glossary / T

Tranexamic Acid

A gentle, well-tolerated brightening active that helps fade the look of stubborn pigmentation and post-blemish marks.

tranexamic acid, TXA, trans-4-(aminomethyl)cyclohexanecarboxylic acid

Pigmentation & dark spots

    What it does

    Tranexamic acid, or TXA, is a synthetic derivative of the amino acid lysine, first used in medicine to control bleeding. In skincare it has become one of the most valued ingredients for uneven tone: it helps fade the look of dark marks left after breakouts or sun exposure, and stubborn pigmentation, and brightens the complexion overall. It is generally well tolerated, including by sensitive skin and deeper skin tones, and can often be used long term.

    How it works

    UV exposure and inflammation convert an inactive enzyme, plasminogen, into plasmin in skin cells, and plasmin signals the pigment cells (melanocytes) to make and pass on more melanin. Tranexamic acid has been studied for its effect on that conversion, which is why it is used to help even the look of skin tone rather than to bleach the skin. It is found in serums, toners and creams, and results build gradually, usually over six to twelve weeks of consistent use.

    MG says

    Tranexamic acid is one of the gentlest ways to help fade the look of stubborn pigmentation at home: use it once or twice daily, layer it with vitamin C or niacinamide, and give it six to twelve weeks, with SPF every morning. For stubborn or hormonal pigmentation, which some heat-based lasers can aggravate, the studios offer Cosmelan and Dermamelan peels with a dedicated home-care regimen, to help even the look of skin tone.

    Cautions

    Topical tranexamic acid is generally well tolerated; the most common reactions are mild, short-lived redness or dryness. Patch test first if your skin is reactive, and wear SPF daily. If you're pregnant, trying to conceive or breastfeeding, check with your doctor, midwife or pharmacist before using it. Oral tranexamic acid is a medicine rather than a skincare step, and should only be taken on medical advice.

    Regional notes

    Australia: Skincare may contain up to 3% tranexamic acid; stronger preparations, and all oral forms, are prescription-only (Schedule 4).